Sanguinarine Attenuates Collagen-Induced Platelet Activation and Thrombus Formation
نویسندگان
چکیده
منابع مشابه
Petasites japonicus Ethanol Extract Inhibited Collagen-Induced Platelet Aggregation and Thrombus Formation in Rats
Petasites japonicus (P. japonicus), a perennial plant of Asteraceae family, has been reported for antioxidant, anti-obesity and anti-allergic effects. However, the anti-platelet and anti-thrombotic activities of this plant were remained unclear. Therefore, this study aimed to portray the anti-platelet and anti-thrombotic properties of P. japonicus ethanol extract (PJET) in rats. PJET (31 -500 μ...
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severe homozygous von Willebrand factor (vWF)-deficient pigs (vWF<3%) (n=6), and heterozygous vWF-deficient pigs (vWF=24%) (n=2). Thrombus formation was measured by autologous "'In-platelet labeling and by ultrastructural morphology. Heparinized and native blood from these pigs was perfused over the substrate for 3 and 5 minutes at local shear rates from 212 to 3,380/sec. On collagen type I exp...
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ژورنال
عنوان ژورنال: Biomedicines
سال: 2021
ISSN: 2227-9059
DOI: 10.3390/biomedicines9050444